SCHEMBL7090190

SCHEMBL7090190

O=C(NC(O)C(F)(F)F)c1snc(Cl)c1Cl

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7471489 0.74 CNR2 (0.30)
SCHEMBL28911168 0.73 POLB (0.31) SMN1; SMN2
SCHEMBL7067333 0.71 CHRM4 (0.36) ALDH1A1HTTSMN1; SMN2
SCHEMBL7067885 0.71 EGLN1 (0.44) SMN1; SMN2
SCHEMBL7085349 0.71 OGG1 (0.41) ALDH1A1HTTSMN1; SMN2
SCHEMBL7088346 0.71 SMN1; SMN2 (0.38) ALDH1A1HTTSMN1; SMN2
SCHEMBL14382722 0.70 ALDH1A1 (0.51) ALDH1A1SMN1; SMN2
SCHEMBL13515520 0.69 CHRM4 (0.32)
SCHEMBL7067322 0.69 ALDH1A1 (0.36) ALDH1A1HTTSMN1; SMN2
SCHEMBL7067663 0.69 TAS1R3 (0.42) ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030176477-A1 Isothiazolecarboxylic acid derivatives and their use as microbicides NIHON BAYER AGROCHEM, K.K. (JP) 2003-09-18 US disclosed
EP-1261592-A1 ISOTHIAZOLECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS MICROBICIDES NIHON BAYER AGROCHEM K.K. (JP) 2002-12-04 EP disclosed
WO-2001055124-A1 ISOTHIAZOLECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS MICROBICIDES NIHON BAYER AGROCHEM K.K. (JP) 2001-08-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030176477-A1 Isothiazolecarboxylic acid derivatives and their use as microbicides IFNG, MPO, CD14 ALDH1A1 430/4885HTT 4571/4885SMN1; SMN2 4824/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.