Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.44 |
| ▸ | GGT1 | P19440 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11418287 | 0.86 | ALDH1A1 (0.51) | PTGER1ALDH1A1KMT2APTK2BMRGPRX4 | |
| SCHEMBL2345074 | 0.86 | PTGER1 (0.52) | PTGER1KMT2AMRGPRX4TSHRHTT | |
| SCHEMBL25289272 | 0.84 | ALDH1A1 (0.53) | PTGER1ALDH1A1KMT2APTK2B | |
| SCHEMBL27972938 | 0.84 | PTGER1 (0.51) | PTGER1ALDH1A1KMT2APTK2BMRGPRX4 | |
| SCHEMBL6049923 | 0.83 | PTGER1 (0.50) | PTGER1ALDH1A1KMT2APTK2BMRGPRX4 | |
| SCHEMBL2340348 | 0.83 | KMT2A (0.51) | PTGER1ALDH1A1KMT2APTK2BKDM4E | |
| SCHEMBL23748604 | 0.82 | CNR2 (0.48) | PTGER1ALDH1A1KMT2APTK2B | |
| SCHEMBL7997485 | 0.81 | PTGER1 (0.49) | PTGER1ALDH1A1KMT2APTK2BMRGPRX4 | |
| SCHEMBL4101951 | 0.81 | KMT2A (0.51) | PTGER1ALDH1A1KMT2APTK2BKDM4E | |
| SCHEMBL410077 | 0.81 | PTGER1 (0.76) | PTGER1MRGPRX4HTTMAPK1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607373-A1 | TRISUBSTITUTED PHENYL DERIVATIVES AS SELECTIVE PHOSPHODIESTERASE IV INHIBITORS. | CELLTECH LTD (GB) | 1994-07-27 | — | — | EP | disclosed |
| WO-1993025517-A1 | TRISUBSTITUTED PHENYL DERIVATIVES AS SELECTIVE PHOSPHODIESTERASE IV INHIBITORS | CELLTECH LIMITED (GB) | 1993-12-23 | — | — | WO | disclosed |