Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7467991 | 0.75 | NR1H4 (0.38) | KDM4ELMNAHTTSMN1; SMN2MAPT | |
| SCHEMBL5444674 | 0.75 | MEN1 (0.81) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL7469162 | 0.74 | POLB (0.36) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL9308540 | 0.71 | MEN1 (0.45) | MEN1KMT2A | |
| SCHEMBL9040172 | 0.71 | AGTR2 (0.49) | — | |
| SCHEMBL9040197 | 0.71 | AGTR1 (0.42) | — | |
| SCHEMBL30783416 | 0.71 | MEN1 (1.00) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL377486 | 0.71 | MEN1 (1.00) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL9309979 | 0.70 | AGTR2 (0.35) | — | |
| SCHEMBL7472677 | 0.70 | RAB9A (0.36) | LMNAHTTSMN1; SMN2MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016071-A1 | HETEROCYCLIC DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-19 | — | — | WO | disclosed |