Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5670577 | 0.82 | L3MBTL1 (0.58) | L3MBTL1MEN1KMT2AGAAMAPK1 | |
| SCHEMBL2101384 | 0.80 | L3MBTL1 (0.63) | L3MBTL1MEN1KMT2AGAACYP3A4 | |
| SCHEMBL17055837 | 0.80 | L3MBTL1 (0.63) | L3MBTL1MEN1KMT2AGAACYP3A4 | |
| SCHEMBL3597209 | 0.80 | L3MBTL1 (0.63) | L3MBTL1MEN1KMT2AGAACYP3A4 | |
| SCHEMBL18209180 | 0.80 | L3MBTL1 (0.63) | L3MBTL1MEN1KMT2AGAACYP3A4 | |
| SCHEMBL7468675 | 0.80 | L3MBTL1 (0.63) | L3MBTL1MEN1KMT2AGAACYP3A4 | |
| SCHEMBL7476434 | 0.80 | L3MBTL1 (0.63) | L3MBTL1MEN1KMT2AGAACYP3A4 | |
| SCHEMBL20414554 | 0.80 | L3MBTL1 (0.63) | L3MBTL1MEN1KMT2AGAACYP3A4 | |
| SCHEMBL7460746 | 0.80 | L3MBTL1 (0.67) | L3MBTL1MEN1KMT2AGAAHSD17B10 | |
| SCHEMBL7473268 | 0.79 | L3MBTL1 (0.41) | L3MBTL1MEN1KMT2AGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-B1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO MCNEIL PHARM INC (US) | 2002-12-18 | — | — | EP | disclosed |
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |