SCHEMBL747286

SCHEMBL747286

OC(c1ccccc1)C1(c2ccccc2)OCCO1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 5/20 0.35
OPRM1 P35372 3/20 0.35
OPRD1 P41143 2/20 0.35
OPRK1 P41145 2/20 0.35
SRC P12931 1/20 0.34
CYP1A2 P05177 1/20 0.34
TSHR P16473 3/20 0.34
ALDH1A1 P00352 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
LMNA P02545 3/20 0.33
MAPK1 P28482 1/20 0.33
GRIN2B Q13224 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
HPGD P15428 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL747102 0.93 OPRM1 (0.33) OPRL1OPRM1OPRD1OPRK1SRC
SCHEMBL748992 0.80 ALDH1A1 (0.35) OPRL1OPRM1ALDH1A1L3MBTL1
SCHEMBL9341766 0.78 CYP1A2 (0.39) OPRL1OPRM1OPRD1OPRK1CYP1A2
SCHEMBL8617290 0.78 ICMT (0.31) OPRL1OPRM1OPRD1OPRK1
SCHEMBL747106 0.77 ALDH1A1 (0.34) OPRL1OPRM1OPRD1OPRK1ALDH1A1
SCHEMBL747694 0.76 ALDH1A1 (0.36) ALDH1A1
SCHEMBL747107 0.75 HTR1A (0.35)
SCHEMBL749250 0.75 OPRL1 (0.34) OPRL1OPRM1OPRD1OPRK1ALDH1A1
SCHEMBL31618321 0.74 ALDH1A1 (0.38) SRCCYP1A2TSHRALDH1A1L3MBTL1
SCHEMBL751089 0.74 ALDH1A1 (0.34) OPRL1OPRM1OPRD1OPRK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2452984-A1 Degassing Compositions for Curable Coatings Troy Technology Corporation, Inc. (US) 2012-05-16 EP disclosed
EP-2152812-B1 DEGASSING COMPOSITIONS FOR CURABLE COATINGS TROY TECHNOLOGY CORP INC (US) 2012-03-21 EP disclosed
US-7842745-B2 Degassing compositions for curable coatings TROY CORPORATION (US) 2010-11-30 US disclosed
US-7842745-B2 Degassing compositions for curable coatings TROY CORPORATION (US) 2010-11-30 US disclosed
US-20100204373-A1 Degassing compositions for curable coatings TROY CORPORATION 2010-08-12 US disclosed
US-20100204373-A1 Degassing compositions for curable coatings TROY CORPORATION 2010-08-12 US disclosed
EP-2152812-A1 DEGASSING COMPOSITIONS FOR CURABLE COATINGS Troy Technology Corporation, Inc. (US) 2010-02-17 EP disclosed
US-7615585-B2 Degassing compositions for curable coatings TROY CORPORATION (US) 2009-11-10 US disclosed
US-7615585-B2 Degassing compositions for curable coatings TROY CORPORATION (US) 2009-11-10 US disclosed
US-7615585-B2 Degassing compositions for curable coatings TROY CORPORATION (US) 2009-11-10 US disclosed
US-20090023847-A1 Degassing compositions for curable coatings TROY CORPORATION 2009-01-22 US disclosed
US-20090023847-A1 Degassing compositions for curable coatings TROY CORPORATION 2009-01-22 US disclosed
US-20090023847-A1 Degassing compositions for curable coatings TROY CORPORATION 2009-01-22 US disclosed
WO-2008130538-A1 DEGASSING COMPOSITIONS FOR CURABLE COATINGS TROY TECHNOLOGY CORPORATION, INC. (US) 2008-10-30 WO disclosed