SCHEMBL749250

SCHEMBL749250

CC1COC(c2ccccc2)(C(O)c2ccccc2)O1

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 4/20 0.34
OPRM1 P35372 3/20 0.34
CHRNB2 P17787 1/20 0.34
SLC6A2 P23975 1/20 0.34
CHRNB4 P30926 1/20 0.34
CHRNA3 P32297 1/20 0.34
CHRNA4 P43681 1/20 0.34
SLC6A3 Q01959 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
LMNA P02545 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
OPRD1 P41143 1/20 0.31
OPRK1 P41145 1/20 0.31
GRIN2B Q13224 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL748992 0.85 ALDH1A1 (0.35) OPRL1OPRM1CHRNB2SLC6A2CHRNB4
SCHEMBL751246 0.82 OPRL1 (0.33) OPRL1OPRM1CHRNB2SLC6A2CHRNB4
SCHEMBL747100 0.82 ADRA1A (0.37) OPRL1OPRM1LMNAOPRD1OPRK1
SCHEMBL747277 0.79 PTGS2 (0.37) GRIN2B
SCHEMBL749051 0.79 HTR1A (0.36)
SCHEMBL751087 0.79 LMNA (0.36) OPRL1OPRM1L3MBTL1LMNAALDH1A1
SCHEMBL751247 0.77 HTR1A (0.37) L3MBTL1
SCHEMBL749306 0.77 OPRM1 (0.36) OPRL1OPRM1LMNAOPRD1OPRK1
SCHEMBL748893 0.77 OPRM1 (0.35) OPRL1OPRM1ALDH1A1OPRD1OPRK1
SCHEMBL750087 0.76 OPRM1 (0.36) OPRL1OPRM1ALDH1A1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2452984-A1 Degassing Compositions for Curable Coatings Troy Technology Corporation, Inc. (US) 2012-05-16 EP claimed
EP-2152812-B1 DEGASSING COMPOSITIONS FOR CURABLE COATINGS TROY TECHNOLOGY CORP INC (US) 2012-03-21 EP claimed
US-7615585-B2 Degassing compositions for curable coatings TROY CORPORATION (US) 2009-11-10 US claimed
US-20090023847-A1 Degassing compositions for curable coatings TROY CORPORATION 2009-01-22 US claimed
EP-2452984-A1 Degassing Compositions for Curable Coatings Troy Technology Corporation, Inc. (US) 2012-05-16 EP disclosed
EP-2152812-B1 DEGASSING COMPOSITIONS FOR CURABLE COATINGS TROY TECHNOLOGY CORP INC (US) 2012-03-21 EP disclosed
US-7842745-B2 Degassing compositions for curable coatings TROY CORPORATION (US) 2010-11-30 US disclosed
US-20100204373-A1 Degassing compositions for curable coatings TROY CORPORATION 2010-08-12 US disclosed
US-7615585-B2 Degassing compositions for curable coatings TROY CORPORATION (US) 2009-11-10 US disclosed
US-20090023847-A1 Degassing compositions for curable coatings TROY CORPORATION 2009-01-22 US disclosed