SCHEMBL7473519

SCHEMBL7473519

Cc1ccccc1CON1C(C)(C)CC2(CC1(C)C)OCCO2

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP2A13 Q16696 1/20 0.38
ALDH1A1 P00352 1/20 0.36
TSHR P16473 1/20 0.36
HTT P42858 1/20 0.36
MAPK1 P28482 1/20 0.35
MAOB P27338 1/20 0.35
ADRA2A P08913 1/20 0.34
ADRA2B P18089 1/20 0.34
ADRA2C P18825 1/20 0.34
KMT2A Q03164 1/20 0.33
LMNA P02545 1/20 0.31
ACHE P22303 1/20 0.31
TACR1 P25103 2/20 0.31
ICMT O60725 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7474629 0.77 KMT2A (0.41) CYP2A13ALDH1A1TSHRHTTMAOB
SCHEMBL9039574 0.75 KMT2A (0.41) CYP2A13ALDH1A1MAOBADRA2AADRA2B
SCHEMBL9354355 0.72 CYP2A13 (0.33) CYP2A13TSHRADRA2AADRA2BADRA2C
SCHEMBL6548888 0.69 ADRA2A (0.35) CYP2A13ALDH1A1TSHRHTTMAOB
SCHEMBL7476946 0.69 SLC2A1 (0.35) CYP2A13KMT2AACHE
SCHEMBL7562061 0.69 TSHR (0.43) ALDH1A1TSHRHTTMAOBKMT2A
SCHEMBL7480880 0.68 TSHR (0.56) ALDH1A1TSHRHTTMAOBKMT2A
SCHEMBL9244012 0.67 TSHR (0.61) ALDH1A1TSHRHTTMAOBKMT2A
SCHEMBL7475382 0.67 SLC2A1 (0.38)
SCHEMBL9240251 0.66 HTT (0.39) ALDH1A1TSHRHTTMAOBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5096950-A N-alkoxypiperidines CIBA-GEIGY CORPORATION (US) 1992-03-17 US claimed
EP-0467851-A1 Stabilized monomer compositions CIBA-GEIGY AG (CH) 1992-01-22 EP claimed
US-5004770-A Light, heat, and oxygen resistant CIBA-GEIGY CORPORATION (US) 1991-04-02 US claimed
EP-0309402-B2 N-substituted hindered amine stabilizers CIBA SC HOLDING AG (CH) 2002-06-12 EP disclosed
EP-0309402-B1 N-substituted hindered amine stabilizers CIBA GEIGY AG (CH) 1995-01-11 EP disclosed
US-5204473-A O-substituted N-hydroxy hindered amine stabilizers CIBA-GEIGY CORPORATION (US) 1993-04-20 US disclosed
US-5096950-A N-alkoxypiperidines CIBA-GEIGY CORPORATION (US) 1992-03-17 US disclosed
EP-0467851-A1 Stabilized monomer compositions CIBA-GEIGY AG (CH) 1992-01-22 EP disclosed
US-5004770-A Light, heat, and oxygen resistant CIBA-GEIGY CORPORATION (US) 1991-04-02 US disclosed
US-4921962-A REACTION OF AMINE WITH HYDROPEROXIDE CIBA-GEIGY CORPORATION (US) 1990-05-01 US disclosed