Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | THPO | P40225 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465106 | 0.88 | CHRNB2 (0.44) | CYP1A2CYP3A4CYP2D6NFKB1HRH1 | |
| SCHEMBL7477201 | 0.88 | CHRNB2 (0.44) | CYP1A2CYP3A4CYP2D6NFKB1HRH1 | |
| SCHEMBL7468711 | 0.85 | SIGMAR1 (0.46) | SIGMAR1HRH1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7467890 | 0.84 | SLC6A1 (0.45) | SIGMAR1HRH1ALDH1A1LMNA | |
| SCHEMBL7603812 | 0.82 | LTA4H (0.46) | SIGMAR1HRH1 | |
| Hydrochloric Acid SCHEMBL8181412 | 0.81 | LTA4H (0.46) | SIGMAR1HRH1 | |
| SCHEMBL7463247 | 0.80 | ALDH1A1 (0.51) | MEN1ALDH1A1LMNAMAPTTHRB | |
| SCHEMBL7472371 | 0.80 | LTA4H (0.47) | SIGMAR1HRH1 | |
| SCHEMBL7603305 | 0.79 | LTA4H (0.45) | SIGMAR1HRH1 | |
| Hydrochloric Acid SCHEMBL7464493 | 0.79 | LTA4H (0.46) | SIGMAR1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0851865-B1 | 12H-Dibenzo[d,g][1,3]dioxocine derivatives | NOVO NORDISK AS (DK) | 2002-07-17 | — | — | EP | claimed |