Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.30 |
| ▸ | F11 | P03951 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7461868 | 0.95 | ABCB1 (0.32) | PYGLABCB1ABL1SRCNR4A1 | |
| SCHEMBL7469597 | 0.90 | PYGL (0.32) | PYGLF11 | |
| SCHEMBL7473629 | 0.89 | P4HB (0.34) | ABCB1ENPP1F11 | |
| SCHEMBL7460763 | 0.89 | KDM4E (0.37) | — | |
| SCHEMBL7463553 | 0.89 | KDM4E (0.36) | — | |
| SCHEMBL7459606 | 0.88 | ABL1 (0.32) | PYGLABCB1ABL1SRC | |
| SCHEMBL7475427 | 0.88 | KMT2A (0.33) | PYGLABCB1F11 | |
| SCHEMBL6627433 | 0.88 | MAPT (0.38) | PYGLABCB1 | |
| SCHEMBL7466678 | 0.86 | GABRA1 (0.34) | — | |
| SCHEMBL7458517 | 0.86 | P4HB (0.34) | ABCB1ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656360-B1 | TRIFLUOROMETHYLPYRROLOINDOLE CARBOXYLIC ESTER DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | KYORIN SEIYAKU KK (JP) | 2002-11-20 | — | — | EP | disclosed |
| US-5629430-A | ANTICARCINOGENIC AGENTS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1997-05-13 | — | — | US | disclosed |
| EP-0656360-A1 | TRIFLUOROMETHYLPYRROLOINDOLE CARBOXYLIC ESTER DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1995-06-07 | — | — | EP | disclosed |