Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 5/20 | 0.51 |
| ▸ | PLAU | P00749 | 2/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7477507 | 0.84 | CA12 (0.46) | SMN1; SMN2MAPT | |
| SCHEMBL7481379 | 0.83 | ALDH1A1 (0.46) | SMN1; SMN2MAPT | |
| SCHEMBL27583585 | 0.83 | LMNA (0.47) | ELANESMN1; SMN2MAPT | |
| SCHEMBL7473999 | 0.82 | PPARG (0.49) | — | |
| SCHEMBL13299386 | 0.81 | KCNJ1 (0.53) | PLAUPLGSMN1; SMN2MAPT | |
| SCHEMBL7474367 | 0.81 | MAOA (0.43) | MAPT | |
| SCHEMBL7947015 | 0.80 | CYP1A2 (0.48) | PLAUNOD2NOD1ELANESMN1; SMN2 | |
| SCHEMBL7478282 | 0.80 | TSHR (0.42) | ELANESMN1; SMN2MAPT | |
| SCHEMBL3507258 | 0.80 | GAA (0.45) | SERPINE1PLAUNOD2NOD1ELANE | |
| SCHEMBL28614458 | 0.79 | SERPINE1 (0.49) | SERPINE1PLAUPLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210343-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | AstraZeneca AB (SE) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001012187-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2001-02-22 | — | — | WO | disclosed |