Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7477071 | 0.86 | THRA (0.52) | BCL2MCL1KDM4EMEN1KMT2A | |
| SCHEMBL7471302 | 0.85 | TSHR (0.43) | TSHRBCL2MCL1KDM4EALDH1A1 | |
| SCHEMBL7477507 | 0.85 | CA12 (0.46) | MAOAMAOBTSHRBCL2MCL1 | |
| SCHEMBL7481379 | 0.84 | ALDH1A1 (0.46) | TSHRKDM4EBRD4ALDH1A1HPGD | |
| SCHEMBL27583585 | 0.84 | LMNA (0.47) | TSHRKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL7473999 | 0.83 | PPARG (0.49) | TSHRBCL2MCL1 | |
| SCHEMBL7478282 | 0.82 | TSHR (0.42) | TSHRKDM4ELMNAALDH1A1HPGD | |
| SCHEMBL7474077 | 0.81 | SERPINE1 (0.51) | MAPT | |
| SCHEMBL7483021 | 0.80 | PPARD (0.58) | MAOBBCL2MCL1MEN1KMT2A | |
| SCHEMBL7482851 | 0.80 | PPARG (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1379774-A | Compounds | ASTRAZENECA AB (SE) | 2002-11-13 | — | — | CN | disclosed |
| EP-1210343-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | AstraZeneca AB (SE) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001012187-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2001-02-22 | — | — | WO | disclosed |
| EP-0949921-A1 | THROMBIN INHIBITORS | Merck & Co., Inc. (US) | 1999-10-20 | — | — | EP | disclosed |
| EP-0949921-A4 | — | — | 1999-10-20 | — | — | EP | disclosed |
| WO-1998006396-A1 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 1998-02-19 | — | — | WO | disclosed |