Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.46 |
| ▸ | HPGD | P15428 | 10/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27486058 | 0.81 | KDM4E (0.52) | ALDH1A1HPGDKDM4EMAPTRAB9A | |
| SCHEMBL840117 | 0.79 | ALDH1A1 (0.61) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL16511523 | 0.76 | ALDH1A1 (0.49) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL652047 | 0.75 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4EMAPTGAA | |
| SCHEMBL31493861 | 0.74 | KDM4E (0.61) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL7466281 | 0.74 | MMP2 (0.45) | ALDH1A1HPGDKDM4EMAPTRAB9A | |
| SCHEMBL12635358 | 0.74 | KDM4E (0.61) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL7474161 | 0.73 | ALDH1A1 (0.41) | ALDH1A1HPGDKDM4ELMNAMAPT | |
| SCHEMBL21296300 | 0.72 | METAP2 (0.50) | ALDH1A1HPGDKDM4EMAPTGAA | |
| SCHEMBL4523553 | 0.72 | MYC (0.48) | ALDH1A1HPGDKDM4ELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877185-A | THERAPY FOR CANCER OR RETROVIRUS | OCTAMER, INC. (US) | 1999-03-02 | — | — | US | disclosed |
| WO-1996022791-A9 | NOVEL SYNERGISTIC COMPOSITIONS USEFUL AS ANTI-TUMOR OR ANTI-RETROVIRAL AGENTS | — | 1996-10-03 | — | — | WO | disclosed |
| WO-1996022791-A1 | NOVEL SYNERGISTIC COMPOSITIONS USEFUL AS ANTI-TUMOR OR ANTI-RETROVIRAL AGENTS | OCTAMER, INC. (US) | 1996-08-01 | — | — | WO | disclosed |