Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 3/20 | 0.35 |
| ▸ | MMP9 | P14780 | 3/20 | 0.35 |
| ▸ | MMP12 | P39900 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | MMP14 | P50281 | 2/20 | 0.33 |
| ▸ | MMP16 | P51512 | 2/20 | 0.33 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9235115 | 0.78 | SIRT1 (0.47) | MMP2MMP9MMP12PTGS2PTGS1 | |
| SCHEMBL10622791 | 0.76 | HPGD (0.47) | HTTPTGS2PTGS1MAPTSIRT1 | |
| SCHEMBL331001 | 0.74 | MIF (0.46) | HSD17B10MIFHTTMAPTSIRT1 | |
| SCHEMBL15902948 | 0.73 | PDE7A (0.47) | HSD17B10MIFMAPT | |
| SCHEMBL7475089 | 0.72 | MIF (0.42) | HSD17B10MIFMMP2MMP9MMP12 | |
| SCHEMBL10622715 | 0.72 | PDE7A (0.57) | HTTMAPTGAA | |
| SCHEMBL5954570 | 0.68 | MIF (0.64) | HSD17B10MIFMAPT | |
| SCHEMBL323934 | 0.67 | MMP2 (0.67) | MMP2MMP9MMP12PTGS2GAA | |
| SCHEMBL9419835 | 0.67 | MEN1 (0.49) | MMP2MMP9MMP12PTGS2PTGS1 | |
| SCHEMBL2204495 | 0.65 | PTGS2 (0.56) | HSD17B10MMP2MMP9MMP12PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4771062-A | ENZYME INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-13 | — | — | US | disclosed |