Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | GAA | P10253 | 4/20 | 0.53 |
| ▸ | HTR6 | P50406 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 9/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | CLK3 | P49761 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468278 | 0.97 | ALDH1A1 (0.56) | ALDH1A1MAPTGAAHTR6MAPK1 | |
| SCHEMBL7464189 | 0.86 | MAPT (0.56) | ALDH1A1MAPTGAAHTR6MAPK1 | |
| SCHEMBL7470206 | 0.86 | EGFR (0.52) | ALDH1A1MAPTGAAHTR6LMNA | |
| SCHEMBL7468292 | 0.85 | LMNA (0.46) | ALDH1A1MAPTMAPK1LMNASMN1; SMN2 | |
| SCHEMBL7473662 | 0.83 | USP10 (0.47) | ALDH1A1MAPTGAAHTR6LMNA | |
| SCHEMBL7468826 | 0.82 | EGFR (0.56) | ALDH1A1MAPTGAAHTR6MAPK1 | |
| SCHEMBL7467064 | 0.81 | HTR6 (0.52) | ALDH1A1MAPTGAAHTR6MAPK1 | |
| SCHEMBL7465985 | 0.81 | PDE5A (0.55) | ALDH1A1MAPTMAPK1LMNASMN1; SMN2 | |
| SCHEMBL7475796 | 0.81 | LMNA (0.49) | ALDH1A1MAPTMAPK1LMNAHPGD | |
| SCHEMBL7476400 | 0.80 | MAPT (0.41) | ALDH1A1MAPTGAAHTR6MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |