Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7479670 | 0.78 | MEN1 (0.36) | ALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL7482378 | 0.78 | ALDH1A1 (0.37) | ALDH1A1LMNAMAPTGAANPSR1 | |
| SCHEMBL7475018 | 0.78 | KDM4E (0.32) | ALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL7478089 | 0.77 | KDM4E (0.32) | ALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL7478519 | 0.77 | ALDH1A1 (0.33) | ALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL7477896 | 0.77 | MEN1 (0.33) | ALDH1A1LMNAMAPTGAANPSR1 | |
| SCHEMBL7474346 | 0.77 | NPC1 (0.32) | ALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL7478235 | 0.76 | ADORA2B (0.31) | — | |
| SCHEMBL7476209 | 0.76 | NOTUM (0.38) | ALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL7485767 | 0.76 | LMNA (0.32) | ALDH1A1LMNAMAPTGAANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0742218-B1 | PYRROLOPYRIDAZINE DERIVATIVE | SANKYO CO (JP) | 2002-12-04 | — | — | EP | disclosed |
| US-6063782-A | Pyrrolopyridazine derivatives | SANKYO COMPANY, LIMITED (JP) | 2000-05-16 | — | — | US | disclosed |
| EP-0742218-A1 | PYRROLOPYRIDAZINE DERIVATIVE | SANKYO COMPANY LIMITED (JP) | 1996-11-13 | — | — | EP | disclosed |