Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.37 |
| ▸ | HPGD | P15428 | 7/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6882657 | 0.87 | L3MBTL1 (0.42) | ALDH1A1KDM4EHPGDKMT2AL3MBTL1 | |
| SCHEMBL7990577 | 0.83 | KMT2A (0.47) | ALDH1A1KDM4EHPGDKMT2AHSD17B10 | |
| SCHEMBL6698677 | 0.81 | ALDH1A1 (0.35) | ALDH1A1KDM4EHPGDKMT2AL3MBTL1 | |
| SCHEMBL7104276 | 0.80 | NSD2 (0.55) | ALDH1A1KDM4EHPGDKMT2AL3MBTL1 | |
| SCHEMBL8666487 | 0.79 | GAA (0.35) | KDM4EHPGDBRD4KMT2AL3MBTL1 | |
| SCHEMBL6866131 | 0.78 | MEN1 (0.48) | ALDH1A1HPGDKMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL6859753 | 0.78 | MEN1 (0.48) | ALDH1A1HPGDKMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL7088459 | 0.77 | ALOX5 (0.41) | ALDH1A1KDM4EALOX15KMT2AL3MBTL1 | |
| SCHEMBL7135873 | 0.75 | NPC1 (0.53) | ALDH1A1KMT2AL3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL6484868 | 0.74 | ALDH1A1 (0.35) | ALDH1A1KDM4EKMT2AHSD17B10HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001068605-A1 | POLYCYCLIC ARYL AND HETEROARYL SUBSTITUTED BENZENES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2001-09-20 | — | — | WO | claimed |