Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7476442 | 0.83 | ALDH1A1 (0.37) | KMT2AHSD17B10KDM4EHPGDNPSR1 | |
| SCHEMBL8669022 | 0.81 | KMT2A (0.46) | KMT2AHSD17B10GAAKDM4EHPGD | |
| SCHEMBL6882657 | 0.80 | L3MBTL1 (0.42) | KMT2AKDM4EHPGDPOLBALDH1A1 | |
| SCHEMBL7088459 | 0.80 | ALOX5 (0.41) | KMT2AHSD17B10KDM4EMLYCDNPSR1 | |
| SCHEMBL6866131 | 0.78 | MEN1 (0.48) | KMT2AHPGDPOLBMEN1ALDH1A1 | |
| SCHEMBL6859753 | 0.78 | MEN1 (0.48) | KMT2AHPGDPOLBMEN1ALDH1A1 | |
| SCHEMBL6484868 | 0.77 | ALDH1A1 (0.35) | KMT2AHSD17B10GAAKDM4EMEN1 | |
| SCHEMBL7104276 | 0.76 | NSD2 (0.55) | KMT2AHSD17B10GAAKDM4EHPGD | |
| SCHEMBL22223496 | 0.74 | POLB (0.57) | KMT2AHSD17B10GAAKDM4EHPGD | |
| SCHEMBL6698677 | 0.74 | ALDH1A1 (0.35) | KMT2AHSD17B10GAAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001087852-A1 | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL URACILS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2001-11-22 | — | — | WO | claimed |