Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.38 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.38 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.38 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472311 | 0.78 | HSD11B1 (0.41) | HSD11B1KDM4EPOLBCYP3A4CYP2C9 | |
| SCHEMBL30513969 | 0.75 | ALDH1A1 (0.56) | HSD11B1KDM4EPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL29039876 | 0.75 | ALDH1A1 (0.56) | HSD11B1KDM4EPOLBL3MBTL1ALDH1A1 | |
| SCHEMBL31092469 | 0.74 | HTR6 (0.57) | HSD11B1KDM4EPOLBCYP3A4CYP2C9 | |
| SCHEMBL1713160 | 0.74 | HTR6 (0.57) | HSD11B1KDM4EPOLBCYP3A4CYP2C9 | |
| SCHEMBL29242564 | 0.74 | KDM4E (0.50) | HSD11B1KDM4EPOLBCYP3A4CYP2C9 | |
| SCHEMBL29468592 | 0.73 | ALDH1A1 (0.55) | HSD11B1KDM4EPOLBCYP3A4CYP2C9 | |
| SCHEMBL475089 | 0.73 | ALDH1A1 (0.55) | HSD11B1KDM4EPOLBCYP3A4CYP2C9 | |
| SCHEMBL13241569 | 0.72 | LMNA (0.52) | HSD11B1KDM4EL3MBTL1ALDH1A1MAPT | |
| SCHEMBL1448262 | 0.72 | SMN1; SMN2 (0.37) | ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194417-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AG (DE) | 2002-04-10 | — | — | EP | disclosed |
| WO-2000078733-A1 | PHENOXY FLUOROPYRIMIDINES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-28 | — | — | WO | disclosed |