SCHEMBL747689

SCHEMBL747689

CCCC(CC)C1COC(c2ccccc2)(C(O)c2ccccc2)O1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 5/20 0.35
OPRD1 P41143 5/20 0.35
OPRK1 P41145 5/20 0.35
OPRL1 P41146 5/20 0.35
AOC3 Q16853 2/20 0.33
LMNA P02545 1/20 0.33
GRIN2B Q13224 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL749571 0.88 OPRM1 (0.34) OPRM1OPRD1OPRK1OPRL1AOC3
SCHEMBL749306 0.88 OPRM1 (0.36) OPRM1OPRD1OPRK1OPRL1AOC3
SCHEMBL750086 0.87 OPRM1 (0.36) OPRM1OPRD1OPRK1OPRL1AOC3
SCHEMBL751087 0.85 LMNA (0.36) OPRM1OPRD1OPRK1OPRL1LMNA
SCHEMBL750091 0.83 OPRM1 (0.39) OPRM1OPRD1OPRK1OPRL1
SCHEMBL750051 0.82 OPRM1 (0.40) OPRM1OPRD1OPRK1OPRL1
SCHEMBL751246 0.81 OPRL1 (0.33) OPRM1OPRD1OPRK1OPRL1LMNA
SCHEMBL751250 0.79 OPRM1 (0.35) OPRM1OPRD1OPRK1OPRL1AOC3
SCHEMBL747100 0.78 ADRA1A (0.37) OPRM1OPRD1OPRK1OPRL1LMNA
SCHEMBL751116 0.78 OPRM1 (0.34) OPRM1OPRD1OPRK1OPRL1AOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2452984-A1 Degassing Compositions for Curable Coatings Troy Technology Corporation, Inc. (US) 2012-05-16 EP claimed
EP-2152812-B1 DEGASSING COMPOSITIONS FOR CURABLE COATINGS TROY TECHNOLOGY CORP INC (US) 2012-03-21 EP claimed
US-20090023847-A1 Degassing compositions for curable coatings TROY CORPORATION 2009-01-22 US claimed
EP-2452984-A1 Degassing Compositions for Curable Coatings Troy Technology Corporation, Inc. (US) 2012-05-16 EP disclosed
EP-2152812-B1 DEGASSING COMPOSITIONS FOR CURABLE COATINGS TROY TECHNOLOGY CORP INC (US) 2012-03-21 EP disclosed
US-7615585-B2 Degassing compositions for curable coatings TROY CORPORATION (US) 2009-11-10 US disclosed
US-20090023847-A1 Degassing compositions for curable coatings TROY CORPORATION 2009-01-22 US disclosed