SCHEMBL751246

SCHEMBL751246

CC(O)C1COC(c2ccccc2)(C(O)c2ccccc2)O1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 3/20 0.33
OPRM1 P35372 2/20 0.33
OPRD1 P41143 1/20 0.33
OPRK1 P41145 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
EPHX1 P07099 1/20 0.31
ADRA2A P08913 1/20 0.31
ADRA2C P18825 1/20 0.31
LMNA P02545 1/20 0.31
HIF1A Q16665 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 2/20 0.30
GLA P06280 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
CHRM2 P08172 2/20 0.30
CHRM4 P08173 2/20 0.30
CHRM5 P08912 2/20 0.30
CHRM1 P11229 2/20 0.30
CHRM3 P20309 2/20 0.30
HTR1A P08908 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL747106 0.86 ALDH1A1 (0.34) OPRL1OPRM1OPRD1OPRK1L3MBTL1
SCHEMBL751087 0.85 LMNA (0.36) OPRL1OPRM1OPRD1OPRK1L3MBTL1
SCHEMBL750086 0.84 OPRM1 (0.36) OPRL1OPRM1OPRD1OPRK1LMNA
SCHEMBL749306 0.83 OPRM1 (0.36) OPRL1OPRM1OPRD1OPRK1LMNA
SCHEMBL749250 0.82 OPRL1 (0.34) OPRL1OPRM1OPRD1OPRK1L3MBTL1
SCHEMBL750091 0.81 OPRM1 (0.39) OPRL1OPRM1OPRD1OPRK1KDM4E
SCHEMBL747689 0.81 OPRM1 (0.35) OPRL1OPRM1OPRD1OPRK1LMNA
SCHEMBL747100 0.80 ADRA1A (0.37) OPRL1OPRM1OPRD1OPRK1LMNA
SCHEMBL750051 0.80 OPRM1 (0.40) OPRL1OPRM1OPRD1OPRK1
SCHEMBL747277 0.77 PTGS2 (0.37) CHRM2CHRM4CHRM5CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2152812-B1 DEGASSING COMPOSITIONS FOR CURABLE COATINGS TROY TECHNOLOGY CORP INC (US) 2012-03-21 EP claimed