Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | FPR1 | P21462 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466008 | 0.82 | MEN1 (0.46) | PYCR1CNR2MAPTKDRPTGER1 | |
| SCHEMBL7468867 | 0.81 | LDHA (0.43) | PYCR1PTGER1TAAR1 | |
| SCHEMBL7471697 | 0.79 | MEN1 (0.46) | CNR2MAOBFPR1MAPT | |
| SCHEMBL21305403 | 0.77 | ALOX5 (0.43) | CNR2GPR55PTGS1PTGS2CNR1 | |
| SCHEMBL27368195 | 0.75 | MAOB (0.39) | CNR2MAOBMAPTP2RX7 | |
| SCHEMBL3152055 | 0.75 | MAPT (0.47) | MAPTALDH1A1 | |
| SCHEMBL19143126 | 0.75 | LTA4H (0.46) | CNR2GPR55PTGS1PTGS2ALDH1A1 | |
| SCHEMBL3890253 | 0.75 | MEN1 (0.51) | MAPTALDH1A1 | |
| SCHEMBL28254917 | 0.75 | SLC5A2 (0.47) | PYCR1MAPTALDH1A1 | |
| SCHEMBL1773044 | 0.74 | IDO1 (0.46) | MAOBMAPTTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757986-B1 | Arylpiperidine and arylpiperazine derivatives and drugs containing the same | SUNTORY LTD (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-5723475-A | Arylpiperidine and arylpiperazine derivatives and medicament containing the same | SUNTORY LIMITED (JP) | 1998-03-03 | — | — | US | disclosed |
| EP-0757986-A1 | ARYLPIPERIDINE AND ARYLPIPERAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1997-02-12 | — | — | EP | disclosed |