Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | FPR1 | P21462 | 2/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL180996 | 0.87 | SLC5A1 (0.46) | MEN1KMT2AL3MBTL1LTA4HHTT | |
| SCHEMBL7846076 | 0.86 | LTA4H (0.52) | LTA4HCNR2SLC5A1IDO1 | |
| SCHEMBL28842002 | 0.84 | LTA4H (0.55) | L3MBTL1LTA4HTDP1NPC1MAPT | |
| SCHEMBL28302613 | 0.83 | L3MBTL1 (0.50) | L3MBTL1LTA4HHTTTDP1NPC1 | |
| SCHEMBL27454169 | 0.80 | CNR2 (0.46) | MEN1KMT2AL3MBTL1LTA4HHTT | |
| SCHEMBL3892695 | 0.80 | TDP1 (0.48) | MEN1KMT2AL3MBTL1LTA4HHTT | |
| SCHEMBL1539299 | 0.79 | ACHE (0.48) | MEN1KMT2AL3MBTL1LTA4HMAPT | |
| SCHEMBL7477576 | 0.79 | PYCR1 (0.41) | MAPTCNR2FPR1MAOB | |
| SCHEMBL7466008 | 0.79 | MEN1 (0.46) | MEN1KMT2AMAPTCNR2 | |
| SCHEMBL23040922 | 0.79 | MAOB (0.51) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757986-B1 | Arylpiperidine and arylpiperazine derivatives and drugs containing the same | SUNTORY LTD (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-5723475-A | Arylpiperidine and arylpiperazine derivatives and medicament containing the same | SUNTORY LIMITED (JP) | 1998-03-03 | — | — | US | disclosed |
| EP-0757986-A1 | ARYLPIPERIDINE AND ARYLPIPERAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME | SUNTORY LIMITED (JP) | 1997-02-12 | — | — | EP | disclosed |