Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K4 | P45985 | 2/20 | 0.49 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | TTK | P33981 | 6/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5762375 | 0.84 | PBRM1 (0.44) | MAP2K4CA1CA2CA9CA12 | |
| SCHEMBL7472841 | 0.83 | HSD17B14 (0.44) | MAP2K4 | |
| SCHEMBL1385903 | 0.83 | PTGS2 (0.41) | MAP2K4MAP2K7 | |
| SCHEMBL7480868 | 0.82 | NPY5R (0.41) | MAP2K4MAP2K7MAOB | |
| SCHEMBL7474871 | 0.82 | MAP2K4 (0.39) | MAP2K4CA12 | |
| SCHEMBL7476723 | 0.82 | PARP1 (0.40) | MAP2K4 | |
| SCHEMBL5323714 | 0.82 | MAPK14 (0.55) | MAP2K4MAP2K7 | |
| SCHEMBL7477875 | 0.82 | CA2 (0.48) | MAP2K4MAP2K7CDK2CA1CA2 | |
| SCHEMBL7476607 | 0.81 | MAPK1 (0.38) | MAP2K4CA12 | |
| SCHEMBL7812428 | 0.80 | MAPK14 (0.55) | MAP2K4CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0509354-B1 | Amino acid derivatives | HOFFMANN LA ROCHE (CH) | 2000-08-23 | — | — | EP | claimed |