Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CDK1 | P06493 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | TDO2 | P48775 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CA11 | O75493 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7477961 | 0.82 | KMT2A (0.49) | ALDH1A1CDK1CDK2KMT2AMEN1 | |
| SCHEMBL13593171 | 0.77 | TUBB4A (0.45) | CDK1CDK2KMT2AMEN1CA1 | |
| SCHEMBL3017326 | 0.77 | AKR1B1 (0.47) | ALDH1A1KMT2AMEN1EGFRSRC | |
| SCHEMBL28902089 | 0.75 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1EGFRSRC | |
| SCHEMBL14136047 | 0.74 | GAA (0.59) | ALDH1A1KMT2AMEN1EGFRSRC | |
| SCHEMBL4612168 | 0.74 | EGFR (0.47) | ALDH1A1CDK1CDK2KMT2AMEN1 | |
| SCHEMBL11336102 | 0.71 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1CDK1CDK2KMT2A | |
| SCHEMBL29484412 | 0.69 | MEN1 (0.45) | ALDH1A1L3MBTL1CDK1CDK2KMT2A | |
| SCHEMBL34468648 | 0.68 | RAPGEF4 (0.58) | ALDH1A1L3MBTL1KMT2ARAPGEF4CA1 | |
| SCHEMBL3624603 | 0.67 | MPO (0.48) | ALDH1A1KMT2AMEN1EGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210343-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | AstraZeneca AB (SE) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001012187-A2 | BENZOIC ACID DERIVATIVES AND THEIR USE AS PPAR RECEPTOR AGONISTS | ASTRAZENECA AB (SE) | 2001-02-22 | — | — | WO | disclosed |