Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | F3 | P13726 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD5 | P21918 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7480606 | 0.99 | DRD1 (0.36) | DRD1HTR1AMEN1KMT2AALDH1A1 | |
| SCHEMBL7487024 | 0.85 | ALDH1A1 (0.38) | MEN1KMT2AALDH1A1PKMKCNMA1 | |
| SCHEMBL7476937 | 0.85 | CYP19A1 (0.42) | DRD1MEN1KMT2AALDH1A1PKM | |
| SCHEMBL7478121 | 0.81 | DRD1 (0.44) | DRD1MEN1KMT2AALDH1A1PKM | |
| SCHEMBL7482604 | 0.81 | KCNMA1 (0.33) | MEN1KMT2AKCNMA1JAK2 | |
| Bromide SCHEMBL7473644 | 0.81 | DRD1 (0.43) | DRD1MEN1KMT2AALDH1A1PKM | |
| Bromide SCHEMBL7475766 | 0.80 | KCNMA1 (0.32) | MEN1KMT2AKCNMA1JAK2 | |
| SCHEMBL7482205 | 0.79 | DRD2 (0.46) | DRD1DRD3CYP19A1DRD2DRD5 | |
| SCHEMBL7478156 | 0.78 | CHRNA7 (0.42) | HTR1AMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL7478986 | 0.78 | CYP1A2 (0.30) | HTR1AMEN1KMT2APKMKCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950056-B1 | N-(PYRIDINYLAMINO)ISOINDOLINES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2002-09-18 | — | — | EP | claimed |
| EP-0950056-A2 | N-(PYRIDINYLAMINO)ISOINDOLINES AND RELATED COMPOUNDS | HOECHST MARION ROUSSEL, INC. (US) | 1999-10-20 | — | — | EP | claimed |
| WO-1998029407-A2 | N-(PYRIDINYLAMINO)ISOINDOLINES FOR TREATING ALZHEIMER'S AND DEPRESSION | HOECHST MARION ROUSSEL, INC. (US) | 1998-07-09 | — | — | WO | claimed |