Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | STAT3 | P40763 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | OGFRL1 | Q5TC84 | 4/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL8073581 | 0.98 | LMNA (0.41) | LMNAALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL9255441 | 0.74 | ALDH1A1 (0.53) | LMNAALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL7484548 | 0.71 | ALDH1A1 (0.50) | LMNAALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL17910548 | 0.66 | ALDH1A1 (0.47) | LMNAALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL22045617 | 0.66 | CYP19A1 (0.39) | LMNAALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL22801901 | 0.65 | ALDH1A1 (0.43) | LMNAALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL9261907 | 0.65 | SMN1; SMN2 (0.43) | LMNAALDH1A1KMT2ASMN1; SMN2OPRM1 | |
| SCHEMBL18148654 | 0.65 | CYP11B2 (0.39) | LMNAALDH1A1KMT2ASMN1; SMN2OPRM1 | |
| SCHEMBL5800826 | 0.65 | TP53 (0.42) | LMNAALDH1A1KMT2ASMN1; SMN2OPRM1 | |
| SCHEMBL8808783 | 0.64 | GRM2 (0.52) | KMT2AHPGDRAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0843681-B1 | HETEROCYCLE-FUSED THIAZOLE DERIVATIVES | YUNGJIN PHARMACEUTICAL CO LTD (KR) | 2002-03-06 | — | — | EP | disclosed |
| EP-0843681-A1 | HETEROCYCLE-FUSED THIAZOLE DERIVATIVES | YUNGJIN PHARMACEUTICAL CO., LTD. (KR) | 1998-05-27 | — | — | EP | disclosed |
| WO-1997003076-A1 | HETEROCYCLE-FUSED THIAZOLE DERIVATIVES | YUNGJIN PHARMACEUTICAL CO., LTD. (KR) | 1997-01-30 | — | — | WO | disclosed |