Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.41 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.41 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.41 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 4/20 | 0.41 |
| ▸ | JAK1 | P23458 | 4/20 | 0.41 |
| ▸ | TYK2 | P29597 | 4/20 | 0.41 |
| ▸ | JAK3 | P52333 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 6/20 | 0.40 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7477456 | 0.85 | GLP1R (0.44) | NPSR1APEX1LGALS8ALDH1A1MAPK1 | |
| SCHEMBL7481673 | 0.84 | TPSAB1 (0.37) | CHEK2TPSAB1TPSD1TPSG1JAK2 | |
| SCHEMBL7477294 | 0.83 | APEX1 (0.44) | NPSR1APEX1TPSAB1TPSD1TPSG1 | |
| SCHEMBL7481685 | 0.82 | CHEK2 (0.36) | CHEK2TPSAB1TPSD1TPSG1JAK2 | |
| SCHEMBL7481691 | 0.82 | PIN1 (0.41) | CHEK2TPSAB1TPSD1TPSG1JAK2 | |
| Hydrochloric Acid SCHEMBL7477525 | 0.82 | PIN1 (0.40) | CHEK2TPSAB1TPSD1TPSG1JAK2 | |
| SCHEMBL7402998 | 0.79 | F10 (0.58) | TPSAB1TPSD1TPSG1F10F2 | |
| SCHEMBL7408823 | 0.78 | F10 (0.59) | TPSAB1TPSD1TPSG1F10F2 | |
| SCHEMBL9028459 | 0.78 | F10 (0.55) | NPSR1CHEK2TPSAB1TPSD1TPSG1 | |
| SCHEMBL7476975 | 0.76 | F2 (0.50) | APEX1TPSAB1TPSD1TPSG1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000020400-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TREATING HEPATITIS C INFECTIONS | AXYS PHARMACEUTICALS, INC. (US) | 2000-04-13 | — | — | WO | disclosed |