Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 9/20 | 0.55 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.55 |
| ▸ | F2 | P00734 | 2/20 | 0.55 |
| ▸ | PLG | P00747 | 1/20 | 0.55 |
| ▸ | PLAU | P00749 | 1/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.55 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.54 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.54 |
| ▸ | F7 | P08709 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 5/20 | 0.44 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.43 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7406681 | 0.93 | F10 (0.68) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL22533832 | 0.88 | MMP2 (0.50) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL9569971 | 0.86 | APEX1 (0.45) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL9598107 | 0.86 | APEX1 (0.45) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL65730 | 0.84 | F10 (0.77) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL7409221 | 0.83 | F10 (0.66) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL4322200 | 0.83 | TPSAB1 (0.78) | F10TPSAB1PRSS1F2PLG | |
| SCHEMBL7050481 | 0.82 | HDAC6 (0.59) | CHEK2 | |
| SCHEMBL22931148 | 0.81 | CHEK2 (0.56) | F10MMP2MMP13CHEK2 | |
| SCHEMBL22121440 | 0.80 | FABP6 (0.51) | PLAUMMP2MMP13CHEK2PKN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0720603-A1 | BIS(AMIDINOBENZIMIDAZOLYL)ALKANES AS ANTIVIRAL AGENTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-07-10 | — | — | EP | disclosed |