Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL7413764 | 0.85 | ESR1 (0.37) | CXCR1HRH3 | |
| SCHEMBL6591057 | 0.82 | LTA4H (0.49) | CHRNB2CHRNA4HRH3 | |
| SCHEMBL7413854 | 0.81 | KDM4E (0.33) | CXCR1CHRNB2HRH3 | |
| SCHEMBL27489539 | 0.81 | ALDH1A1 (0.41) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL7416361 | 0.80 | ALDH1A1 (0.40) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL7667760 | 0.80 | CXCR1 (0.34) | CXCR1HTR2ACHRNB2CHRNA4 | |
| SCHEMBL6589684 | 0.75 | LTA4H (0.44) | — | |
| SCHEMBL6589690 | 0.75 | LTA4H (0.44) | — | |
| SCHEMBL7404714 | 0.74 | GRM5 (0.38) | CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL7669872 | 0.73 | CHRNB2 (0.51) | CXCR1CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950057-B1 | 3-PYRIDYL ENANTIOMERS AND THEIR USE AS ANALGESICS | ABBOTT LAB (US) | 2002-11-13 | — | — | EP | disclosed |
| US-6403575-B1 | ANTI-INFLAMMATORIES | ABBOTT LABORATORIES | 2002-06-11 | — | — | US | disclosed |
| US-6133253-A | NEURONAL CELL DEATH PREVENTORS AND ANTI-INFLAMMATORIES | ABBOTT LABORATORIES (US) | 2000-10-17 | — | — | US | disclosed |