SCHEMBL7479747

SCHEMBL7479747

CCCCCCCCCCCCCCCCCCNC(=O)N1CCCCC1CCOC(=O)NCCCCN(CC)CC

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ACHE P22303 13/20 0.39
NPSR1 Q6W5P4 1/20 0.36
NAAA Q02083 1/20 0.36
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7473548 0.91 ACHE (0.40) ACHENPSR1
SCHEMBL7472666 0.89 ACHE (0.40) ACHE
Hydrochloric Acid SCHEMBL7478950 0.88 ACHE (0.39) ACHE
SCHEMBL7471618 0.87 KDM4E (0.45) ACHEKDM4E
SCHEMBL7479943 0.87 GNAI3 (0.42) ACHE
SCHEMBL7484148 0.87 KDM4E (0.50) ACHEKDM4E
SCHEMBL7482936 0.87 ACHE (0.36) ACHENPSR1NAAA
SCHEMBL7479745 0.85 DPP4 (0.34) NPSR1NAAA
SCHEMBL7481152 0.85 HRH3 (0.44)
SCHEMBL7481061 0.85 NAAA (0.38) NPSR1NAAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0933361-B1 1,2-Di-substituted piperidine derivatives as hair growth promoter SHISEIDO CO LTD (JP) 2002-03-27 EP disclosed
US-6057337-A USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS SHISEIDO CO., LTD. (JP) 2000-05-02 US disclosed
EP-0933361-A1 1,2-Di-substituted piperidine derivatives as hair growth promoter SHISEIDO COMPANY LIMITED (JP) 1999-08-04 EP disclosed