SCHEMBL7473548

SCHEMBL7473548

CCCCCCCCCCCCCCCCCCNC(=O)N1CCCCC1CCOC(=O)NCCCN(CCO)CCO

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACHE P22303 14/20 0.40
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7479747 0.91 ACHE (0.39) ACHENPSR1
SCHEMBL7472666 0.90 ACHE (0.40) ACHE
Hydrochloric Acid SCHEMBL7478950 0.89 ACHE (0.39) ACHE
SCHEMBL7471618 0.86 KDM4E (0.45) ACHE
SCHEMBL7484148 0.86 KDM4E (0.50) ACHE
SCHEMBL7479943 0.86 GNAI3 (0.42) ACHE
SCHEMBL7482936 0.86 ACHE (0.36) ACHENPSR1
SCHEMBL7481152 0.86 HRH3 (0.44)
SCHEMBL7473546 0.84 DPP4 (0.33) NPSR1
SCHEMBL7481061 0.84 NAAA (0.38) NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0933361-B1 1,2-Di-substituted piperidine derivatives as hair growth promoter SHISEIDO CO LTD (JP) 2002-03-27 EP disclosed
US-6057337-A USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS SHISEIDO CO., LTD. (JP) 2000-05-02 US disclosed
EP-0933361-A1 1,2-Di-substituted piperidine derivatives as hair growth promoter SHISEIDO COMPANY LIMITED (JP) 1999-08-04 EP disclosed