Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7484189 | 0.78 | MAPT (0.49) | ALDH1A1EPHX1GAAMAPT | |
| SCHEMBL7475772 | 0.76 | HRH3 (0.42) | ALDH1A1MAPTHRH3 | |
| SCHEMBL7473013 | 0.74 | NAAA (0.47) | EPHX1 | |
| SCHEMBL7470756 | 0.74 | HRH3 (0.40) | ALDH1A1MAPTHRH3 | |
| SCHEMBL7484182 | 0.74 | MAPT (0.45) | TP53ALDH1A1MAPTTSHR | |
| SCHEMBL7480507 | 0.74 | MAPT (0.45) | TP53ALDH1A1EPHX1GAAMAPT | |
| SCHEMBL7474634 | 0.74 | MAPT (0.49) | ALDH1A1EPHX1GAAMAPT | |
| Hydrochloric Acid SCHEMBL7472631 | 0.73 | MAPT (0.49) | ALDH1A1EPHX1GAAMAPT | |
| SCHEMBL3345206 | 0.72 | NAMPT (0.44) | TP53ALDH1A1MAPTHRH3 | |
| SCHEMBL4559188 | 0.70 | HTT (0.53) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933361-B1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| US-6057337-A | USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS | SHISEIDO CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0933361-A1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO COMPANY LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |