Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7479965 | 0.87 | POLB (0.38) | ALDH1A1SMN1; SMN2HRH3 | |
| SCHEMBL7476087 | 0.85 | MMP1 (0.39) | MAPTALDH1A1HRH3 | |
| SCHEMBL7480507 | 0.79 | MAPT (0.45) | MAPTTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL7484236 | 0.77 | NPC1 (0.44) | MAPTTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL27031270 | 0.76 | ALDH1A1 (0.44) | ALDH1A1RAB9ANPC1 | |
| SCHEMBL7479744 | 0.76 | MAPT (0.50) | MAPTTP53MEN1KMT2AKDM4E | |
| SCHEMBL7485723 | 0.76 | FKBP1A (0.40) | TP53ALDH1A1MAPK1NPSR1KDM4E | |
| SCHEMBL7474734 | 0.74 | CASP3 (0.41) | GLAKDM4E | |
| SCHEMBL2489249 | 0.74 | HRH3 (0.56) | MEN1KMT2AALDH1A1MAPK1RAB9A | |
| SCHEMBL9068282 | 0.72 | ALDH1A1 (0.48) | MAPTTP53MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933361-B1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO CO LTD (JP) | 2002-03-27 | — | — | EP | disclosed |
| US-6057337-A | USEFUL FOR CARE, IMPROVEMENT OR PREVENTION OF HAIR LOSS | SHISEIDO CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0933361-A1 | 1,2-Di-substituted piperidine derivatives as hair growth promoter | SHISEIDO COMPANY LIMITED (JP) | 1999-08-04 | — | — | EP | disclosed |