Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 6/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7475918 | 0.97 | STAT3 (0.43) | STAT3NPSR1ALDH1A1SLC2A4ESR1 | |
| Hydrochloric Acid SCHEMBL7475915 | 0.97 | STAT3 (0.43) | STAT3NPSR1ALDH1A1SLC2A4ESR1 | |
| SCHEMBL7480860 | 0.82 | SMN1; SMN2 (0.56) | NPSR1ALDH1A1SMN1; SMN2TSHRLMNA | |
| SCHEMBL7477593 | 0.78 | ESR1 (0.46) | STAT3NPSR1ALDH1A1ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL7481106 | 0.77 | ESR1 (0.45) | STAT3NPSR1ALDH1A1ESR1ESR2 | |
| SCHEMBL29115326 | 0.75 | SMN1; SMN2 (0.44) | ALDH1A1SLC2A4SMN1; SMN2CYP19A1TSHR | |
| SCHEMBL2036237 | 0.68 | L3MBTL1 (0.54) | NPSR1ALDH1A1LMNA | |
| SCHEMBL7481560 | 0.67 | ESR1 (0.44) | ALDH1A1ESR1ESR2ANPEPDPP4 | |
| SCHEMBL7900508 | 0.65 | ESR1 (0.62) | ESR1ESR2ANPEPDPP4 | |
| SCHEMBL31409508 | 0.65 | CYP19A1 (0.50) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0950056-B1 | N-(PYRIDINYLAMINO)ISOINDOLINES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2002-09-18 | — | — | EP | claimed |
| EP-0950056-A2 | N-(PYRIDINYLAMINO)ISOINDOLINES AND RELATED COMPOUNDS | HOECHST MARION ROUSSEL, INC. (US) | 1999-10-20 | — | — | EP | claimed |
| WO-1998029407-A2 | N-(PYRIDINYLAMINO)ISOINDOLINES FOR TREATING ALZHEIMER'S AND DEPRESSION | HOECHST MARION ROUSSEL, INC. (US) | 1998-07-09 | — | — | WO | claimed |