Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8801481 | 0.79 | CACNA1H (0.40) | — | |
| Hydrochloric Acid SCHEMBL22397824 | 0.78 | CACNA1H (0.39) | — | |
| SCHEMBL30720841 | 0.76 | FABP4 (0.30) | FABP4 | |
| SCHEMBL28657102 | 0.72 | P2RX7 (0.33) | — | |
| SCHEMBL5897349 | 0.72 | ALDH1A1 (0.39) | PKM | |
| SCHEMBL28838831 | 0.72 | TAAR1 (0.43) | FABP4PKM | |
| SCHEMBL4314648 | 0.72 | — | — | |
| SCHEMBL8172215 | 0.72 | KIF11 (0.31) | — | |
| SCHEMBL11354258 | 0.70 | FABP4 (0.52) | FABP4 | |
| Hydrochloric Acid SCHEMBL28813143 | 0.70 | TAAR1 (0.41) | FABP4PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1211244-A2 | 4,5-substitued imidazolyl compounds for the treatment of inflammation | G.D. Searle & Co. (US) | 2002-06-05 | — | — | EP | claimed |
| EP-0772601-A1 | 4,5-SUBSTITUTED IMIDAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996003387-A1 | 4,5-SUBSTITUTED IMIDAZOLYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-02-08 | — | — | WO | disclosed |
| EP-0032113-A3 | ANTIINFLAMMATORY 4,5-DIARYL-ALPHA-(POLYHALOALKYL)-1H-IMIDAZOLE-2-METHANOLS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-08-05 | — | — | EP | disclosed |
| EP-0032113-A2 | Antiinflammatory 4,5-diaryl-alpha-(polyhaloalkyl)-1H-imidazole-2-methanols | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-07-15 | — | — | EP | disclosed |