Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.65 |
| ▸ | TP53 | P04637 | 3/20 | 0.65 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.58 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | SRC | P12931 | 1/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
| ▸ | GLS | O94925 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11666704 | 0.80 | RAB9A (0.59) | SMN1; SMN2TP53KMT2AMEN1ALDH1A1 | |
| SCHEMBL11480689 | 0.79 | CSNK2A2 (0.83) | SMN1; SMN2TP53KMT2AMEN1ALDH1A1 | |
| SCHEMBL2664519 | 0.79 | SMN1; SMN2 (0.67) | SMN1; SMN2TP53KMT2AMEN1ALDH1A1 | |
| SCHEMBL10991652 | 0.79 | GLS (0.72) | SMN1; SMN2TP53KMT2AMEN1ALDH1A1 | |
| SCHEMBL7482173 | 0.77 | NPC1 (0.66) | SMN1; SMN2TP53KMT2AMEN1ALDH1A1 | |
| SCHEMBL13093635 | 0.77 | ILK (0.50) | SMN1; SMN2TP53KMT2AMEN1ALDH1A1 | |
| SCHEMBL2664521 | 0.75 | CA1 (0.76) | SMN1; SMN2TP53KMT2AMEN1MAPT | |
| SCHEMBL11473324 | 0.75 | TP53 (0.66) | SMN1; SMN2TP53KMT2AMEN1ALDH1A1 | |
| N-Phenylbenzamide SCHEMBL8651257 | 0.75 | SIRT1 (0.74) | SMN1; SMN2KMT2AMEN1MAPTNPC1 | |
| SCHEMBL9795960 | 0.74 | CA2 (1.00) | SMN1; SMN2TP53MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1064273-B1 | 1,3,4-THIADIAZOLES USEFUL FOR THE TREATMENT OF CMV INFECTIONS | UPJOHN CO (US) | 2002-12-18 | — | — | EP | claimed |
| EP-1064273-B1 | 1,3,4-THIADIAZOLES USEFUL FOR THE TREATMENT OF CMV INFECTIONS | UPJOHN CO (US) | 2002-12-18 | — | — | EP | disclosed |