Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 4/20 | 0.48 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.48 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.46 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.46 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11839181 | 0.86 | CSNK2A1 (0.62) | CA2AKR1B1DGAT1SOAT1LMNA | |
| SCHEMBL4211652 | 0.81 | GAA (0.63) | AKR1B1RAB9AGFERSMN1; SMN2LMNA | |
| SCHEMBL4079253 | 0.80 | FFAR1 (0.57) | AKR1B1LMNAGAATSHRABCC4 | |
| SCHEMBL7388425 | 0.78 | SHMT1 (0.59) | CA2DGAT1SOAT1LMNAGAA | |
| SCHEMBL283587 | 0.77 | CA2 (0.71) | CA2AKR1B1LMNAGAATSHR | |
| SCHEMBL4937928 | 0.77 | CA2 (0.60) | CA2AKR1B1DGAT1SOAT1LMNA | |
| SCHEMBL9890641 | 0.77 | CXCL8 (0.57) | AKR1B1RAB9AGFERSMN1; SMN2PTGS1 | |
| Methane SCHEMBL11698419 | 0.76 | CA2 (0.51) | CA2AKR1B1DGAT1SOAT1LMNA | |
| Methane SCHEMBL7951771 | 0.76 | CA2 (0.69) | CA2AKR1B1LMNAGAATSHR | |
| Hydrochloric Acid SCHEMBL2530252 | 0.76 | CA2 (0.69) | CA2LMNAGAATSHRTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981754-A | TREATMENT OF ANOXIA, ALZHEIMER'S DISEASE, SENILE DEMENTIA, SUBCORTICAL DEMENTIA SUCH AS HUNTINGTON'S CHOREA AND PARKINSON'S DISEASE, DEMENTIA CAUSED BY AIDS, NEUROPATHY | SANOFI (FR) | 1999-11-09 | — | — | US | disclosed |