Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.57 |
| ▸ | FABP4 | P15090 | 1/20 | 0.55 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.54 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.54 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.54 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.53 |
| ▸ | SELL | P14151 | 3/20 | 0.52 |
| ▸ | SELP | P16109 | 3/20 | 0.52 |
| ▸ | SELE | P16581 | 2/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17187933 | 0.88 | PLA2G10 (0.60) | FFAR1FABP4PLA2G10PLA2G2ASELL | |
| SCHEMBL3839813 | 0.86 | PLA2G10 (0.58) | FABP4PLA2G10PLA2G2ASELLSELP | |
| SCHEMBL23296156 | 0.84 | SHMT1 (0.74) | FFAR1FABP4SHMT1SHMT2PLA2G10 | |
| SCHEMBL27999724 | 0.82 | SELP (0.60) | PLA2G10PLA2G2ASELLSELPSELE | |
| SCHEMBL4211652 | 0.81 | GAA (0.63) | FFAR1AKR1B1CYP2A6ABCC4LMNA | |
| SCHEMBL538397 | 0.81 | ABCC4 (0.67) | FFAR1AOC3PLA2G10PLA2G2AAKR1B1 | |
| SCHEMBL7486012 | 0.80 | CA2 (0.59) | AKR1B1ABCC4LMNAGAATSHR | |
| SCHEMBL11839181 | 0.80 | CSNK2A1 (0.62) | SHMT1SHMT2PLA2G10PLA2G2AAKR1B1 | |
| SCHEMBL27894604 | 0.80 | CYP2A6 (0.57) | FFAR1AOC3CYP2A6 | |
| SCHEMBL14340872 | 0.79 | AKR1B1 (0.54) | PLA2G10PLA2G2ASELLSELPSELE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847533-B1 | SIX-MEMBERED HETEROCYCLIC COMPOUND AND THE USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2013-08-14 | — | — | EP | disclosed |
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-18 | — | — | US | disclosed |
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-18 | — | — | US | disclosed |
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-18 | — | — | US | disclosed |
| US-7531533-B2 | 6-Membered heterocyclic compound and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-05-12 | — | — | US | disclosed |
| EP-1847533-A1 | SIX-MEMBERED HETEROCYCLIC COMPOUND AND THE USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2007-10-24 | — | — | EP | disclosed |
| US-20070060590-A1 | 6-Membered heterocyclic compound and use thereof | ASAHI KASEI PHARMA CORPORATION (JP) | 2007-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060590-A1 | 6-Membered heterocyclic compound and use thereof | WNT1, CYP11B2, CYP11B1 | FFAR1 2094/4885FABP4 3535/4885SHMT1 683/4885 |
| US-20090155903-A1 | PHARMACEUTICAL COMPOSITION AND METHOD | APP, PSEN2, PSEN1 | FFAR1 3064/4885FABP4 3844/4885SHMT1 2562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.