Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL745501 | 0.90 | TMEM97 (0.39) | TP53OPRM1OPRD1TMEM97KMT2A | |
| Hydrochloric Acid SCHEMBL752637 | 0.90 | TMEM97 (0.38) | TP53OPRM1OPRD1TMEM97KMT2A | |
| SCHEMBL749603 | 0.89 | TMEM97 (0.39) | TP53OPRM1OPRD1TMEM97KMT2A | |
| SCHEMBL749103 | 0.85 | SRC (0.38) | TP53MAPTKMT2AALDH1A1SIGMAR1 | |
| SCHEMBL746654 | 0.82 | OPRM1 (0.34) | TP53MAPTOPRM1OPRD1TMEM97 | |
| Hydrochloric Acid SCHEMBL751441 | 0.82 | OPRM1 (0.33) | TP53MAPTOPRM1OPRD1TMEM97 | |
| SCHEMBL748523 | 0.81 | LPAR1 (0.38) | OPRM1OPRD1KMT2ACRHBPCRHR2 | |
| SCHEMBL747114 | 0.80 | C5AR1 (0.41) | OPRM1OPRD1TMEM97KMT2ACRHBP | |
| SCHEMBL745512 | 0.80 | OPRM1 (0.34) | TP53MAPTOPRM1OPRD1TMEM97 | |
| SCHEMBL748563 | 0.79 | MBTPS1 (0.39) | TP53MAPTOPRM1OPRD1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8022217-B2 | Compounds suitable as modulators of HDL | CADILA HEALTHCARE LIMITED (IN) | 2011-09-20 | — | — | US | claimed |
| EP-2049493-B1 | COMPOUNDS SUITABLE AS MODULATORS OF HDL | CADILA HEALTHCARE LTD (IN) | 2012-03-21 | — | — | EP | disclosed |
| US-8022217-B2 | Compounds suitable as modulators of HDL | CADILA HEALTHCARE LIMITED (IN) | 2011-09-20 | — | — | US | disclosed |