Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7490703 | 0.95 | PI4KA (0.32) | — | |
| SCHEMBL7488220 | 0.94 | ALDH1A1 (0.34) | — | |
| SCHEMBL7493272 | 0.90 | — | — | |
| SCHEMBL7492334 | 0.72 | XDH (0.36) | HRH3 | |
| SCHEMBL7487251 | 0.71 | — | — | |
| SCHEMBL7488939 | 0.70 | ADORA3 (0.38) | HRH3 | |
| SCHEMBL7545123 | 0.68 | XDH (0.36) | — | |
| SCHEMBL7542834 | 0.67 | XDH (0.38) | — | |
| SCHEMBL5809787 | 0.67 | CCNE2 (0.34) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7490134 | 0.66 | PAK1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915093-B1 | AMIDE DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 2002-11-27 | — | — | EP | disclosed |
| US-6166016-A | Amide derivatives | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-0915093-A1 | AMIDE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1999-05-12 | — | — | EP | disclosed |