Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | CETP | P11597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7545123 | 0.98 | XDH (0.36) | XDHKCNH2ALDH1A1CNR1CNR2 | |
| SCHEMBL7492334 | 0.94 | XDH (0.36) | XDHALDH1A1 | |
| SCHEMBL7491917 | 0.88 | ADORA3 (0.31) | ALDH1A1 | |
| SCHEMBL4566029 | 0.75 | XDH (0.41) | XDHKCNH2ALDH1A1PKMHPGD | |
| SCHEMBL7488220 | 0.73 | ALDH1A1 (0.34) | KCNH2ALDH1A1PKMHPGDGPR84 | |
| SCHEMBL3260370 | 0.73 | XDH (0.39) | XDHKCNH2ALDH1A1GPR84 | |
| SCHEMBL7490703 | 0.72 | PI4KA (0.32) | KCNH2ALDH1A1PKMHPGDGPR84 | |
| SCHEMBL7489509 | 0.71 | GPR84 (0.33) | XDHKCNH2ALDH1A1PKMHPGD | |
| SCHEMBL4566028 | 0.70 | XDH (0.45) | XDHALDH1A1 | |
| SCHEMBL3258117 | 0.69 | XDH (0.41) | XDHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915093-B1 | AMIDE DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 2002-11-27 | — | — | EP | disclosed |
| US-6166016-A | Amide derivatives | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-0915093-A1 | AMIDE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1999-05-12 | — | — | EP | disclosed |