Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.67 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.67 |
| ▸ | GYS1 | P13807 | 13/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.57 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7490663 | 0.84 | SPHK2 (0.56) | SPHK2SPHK1GYS1ALDH1A1 | |
| SCHEMBL14933686 | 0.82 | GYS1 (0.69) | GYS1CYP4F2CYP4A11 | |
| SCHEMBL3575901 | 0.79 | TDP1 (0.66) | ALDH1A1 | |
| SCHEMBL3575904 | 0.79 | TDP1 (0.66) | ALDH1A1 | |
| SCHEMBL6787220 | 0.78 | CA2 (0.59) | — | |
| SCHEMBL6787214 | 0.78 | CA2 (0.59) | — | |
| SCHEMBL6787446 | 0.77 | FKBP1A (0.60) | SPHK2SPHK1 | |
| SCHEMBL32665613 | 0.77 | ALDH1A1 (0.72) | SPHK2ALDH1A1 | |
| SCHEMBL6787454 | 0.77 | FKBP1A (0.60) | SPHK2SPHK1 | |
| SCHEMBL22688327 | 0.77 | ALDH1A1 (0.72) | SPHK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1095839-C | 4,5-diaryl oxazole derivatives | FUJISAWA PHARMACETICAL CO LTD (JP) | 2002-12-11 | — | — | CN | disclosed |
| EP-0842161-B1 | 4,5-DIARYL OXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-09-18 | — | — | EP | disclosed |
| EP-1213285-A2 | 4,5-dipheny-oxazole derivatives and their use as platelet aggregation inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-6300344-B1 | FOR THERAPEUTIC AND/OR PROPHYLACTIC TREATMENT OF ARTERIAL OBSTRUCTION, CEREBROVASCULAR DISEASE, HEPATIC CIRRHOSIS, ARTERIOSCLEROSIS, ISCHEMIC HEART DISEASE, RESTENOSIS AFTER PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY, HYPERTENSION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | disclosed |
| US-5972965-A | USEFUL FOR INHIBITION OF PLATELET AGGREGATION, VASODILATION, ANTIHYPERTENSIVE ACTIVITY AND PROSTAGLANDIN AGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| CN-1196726-A | 4,5-diaryl oxazole derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1998-10-21 | — | — | CN | disclosed |
| EP-0842161-A1 | 4,5-DIARYL OXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997003973-A1 | 4,5-DIARYL OXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-06 | — | — | WO | disclosed |