Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.31 |
| ▸ | MC3R | P41968 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.31 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.31 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7495203 | 0.77 | CDK1 (0.33) | DYRK1ACDK1ADORA2AADORA1 | |
| SCHEMBL7489579 | 0.75 | ADORA2A (0.32) | DYRK1AADORA2AADORA1ADORA2B | |
| SCHEMBL7487478 | 0.72 | ADORA2A (0.34) | DYRK1AADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL7492084 | 0.71 | ADORA2A (0.35) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL7488641 | 0.70 | ADORA2A (0.34) | ADORA2AADORA1ADORA3CNR1ADORA2B | |
| SCHEMBL7484132 | 0.70 | YTHDC1 (0.44) | CDK1ADORA2AYTHDC1ADORA2B | |
| SCHEMBL11916299 | 0.68 | CDK1 (0.34) | DYRK1ACDK1ADORA2AADORA1YTHDC1 | |
| SCHEMBL790146 | 0.64 | CDK1 (0.46) | CDK1ADORA2AADORA1YTHDC1PDE2A | |
| SCHEMBL17813482 | 0.64 | GRM5 (0.41) | DYRK1ACDK1ADORA2AADORA1YTHDC1 | |
| SCHEMBL4402870 | 0.61 | CDK1 (0.66) | CDK1ADORA2AADORA1YTHDC1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915093-B1 | AMIDE DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 2002-11-27 | — | — | EP | disclosed |
| US-6166016-A | Amide derivatives | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-0915093-A1 | AMIDE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1999-05-12 | — | — | EP | disclosed |