Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.51 |
| ▸ | MEN1 | O00255 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | KCNMA1 | Q12791 | 4/20 | 0.47 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.42 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6824013 | 0.84 | KMT2A (0.43) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL7489293 | 0.82 | MEN1 (0.67) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL6920112 | 0.82 | MEN1 (0.46) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL6921876 | 0.81 | CXCR2 (0.66) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL6920949 | 0.79 | ALDH1A1 (0.56) | KMT2AMEN1MAPTRAB9ANPC1 | |
| SCHEMBL6824084 | 0.79 | RORC (0.56) | KMT2AMEN1MAPTNPC1LMNA | |
| SCHEMBL6823084 | 0.78 | KMT2A (0.48) | KMT2AMEN1MAPTNPC1LMNA | |
| SCHEMBL6820172 | 0.78 | MEN1 (0.59) | KMT2AMEN1MAPTLMNAHTT | |
| SCHEMBL6823879 | 0.77 | AKR1C3 (0.44) | KMT2AMEN1MAPTNPC1LMNA | |
| SCHEMBL5595038 | 0.75 | MEN1 (0.74) | KMT2AMEN1MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0896531-A4 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 2002-10-30 | — | — | EP | disclosed |
| EP-0896531-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-02-17 | — | — | EP | disclosed |
| WO-1997029743-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-08-21 | — | — | WO | disclosed |