Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.33 |
| ▸ | XDH | P47989 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7482351 | 0.98 | GPR84 (0.34) | GPR84XDHKCNH2ADORA2BCDK1 | |
| SCHEMBL7487571 | 0.94 | HRH3 (0.34) | XDHCDK1CCNB1HRH3ADORA3 | |
| SCHEMBL7496538 | 0.88 | PDK2 (0.30) | — | |
| SCHEMBL7493590 | 0.81 | — | — | |
| SCHEMBL7491723 | 0.78 | CDK1 (0.39) | XDHKCNH2ADORA2BCDK1CCNB1 | |
| SCHEMBL7490134 | 0.76 | PAK1 (0.39) | XDHCDK1CCNB1PAK1ADORA3 | |
| SCHEMBL8041008 | 0.71 | HRH3 (0.36) | XDHCDK1CCNB1HRH4HRH3 | |
| SCHEMBL7488939 | 0.71 | ADORA3 (0.38) | XDHCDK1CCNB1HRH3PAK1 | |
| SCHEMBL7542834 | 0.71 | XDH (0.38) | GPR84XDHKCNH2ALDH1A1PKM | |
| SCHEMBL7488641 | 0.70 | ADORA2A (0.34) | GPR84XDHKCNH2ADORA2BADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915093-B1 | AMIDE DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 2002-11-27 | — | — | EP | disclosed |
| US-6166016-A | Amide derivatives | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2000-12-26 | — | — | US | disclosed |
| EP-0915093-A1 | AMIDE DERIVATIVES | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1999-05-12 | — | — | EP | disclosed |