Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6176108 | 0.79 | CYP2C9 (0.38) | CYP2C9TSHRHSD11B1ALDH1A1L3MBTL1 | |
| SCHEMBL6174534 | 0.77 | CYP2C9 (0.39) | CYP2C9TSHRHSD11B1ALDH1A1L3MBTL1 | |
| SCHEMBL7481615 | 0.77 | KDM4E (0.37) | POLBTSHRALDH1A1 | |
| SCHEMBL6175954 | 0.70 | HSD11B1 (0.48) | CYP2C9TSHRHSD11B1ALDH1A1L3MBTL1 | |
| SCHEMBL6173671 | 0.69 | HSD11B1 (0.52) | CYP2C9HSD11B1 | |
| SCHEMBL6174556 | 0.68 | OPRD1 (0.44) | CYP2C9CHRM2 | |
| SCHEMBL6175182 | 0.68 | ALDH1A1 (0.46) | CYP2C9TSHRHSD11B1ALDH1A1L3MBTL1 | |
| SCHEMBL6175172 | 0.66 | LDHA (0.38) | CYP2C9HSD11B1ALDH1A1CHRM2 | |
| SCHEMBL6190123 | 0.65 | CYP2C9 (0.37) | CYP2C9POLBHSD11B1ALDH1A1CHRM2 | |
| SCHEMBL6997284 | 0.64 | SIGMAR1 (0.38) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668860-B1 | PYRAN-2-ONES AND 5,6-DIHYDROPYRAN-2-ONES USEFUL FOR TREATING HIV AND OTHER RETROVIRUSES | UPJOHN CO (US) | 2002-09-11 | — | — | EP | claimed |