Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7487295 | 0.93 | LMNA (0.52) | NT5EADORA1BRD4ABCB1MEN1 | |
| SCHEMBL7489710 | 0.91 | KMT2A (0.42) | NT5EMEN1KMT2AACHE | |
| SCHEMBL7685427 | 0.90 | MKNK1 (0.45) | BRD4MEN1MAPTKMT2AACHE | |
| SCHEMBL7491371 | 0.88 | HTR1A (0.42) | BRD4MEN1MAPTKMT2AKDM4E | |
| SCHEMBL8317311 | 0.86 | P2RX3 (0.47) | MAPT | |
| SCHEMBL7540582 | 0.85 | ALDH1A1 (0.37) | NT5EBRD4MAPTLMNAACHE | |
| SCHEMBL7482329 | 0.83 | CACNB4 (0.44) | ADORA1ABCB1MEN1MAPTKMT2A | |
| SCHEMBL7493512 | 0.83 | PTPN1 (0.41) | NT5EADORA1BRD4ABCB1MEN1 | |
| SCHEMBL7491349 | 0.82 | ACHE (0.38) | MAPTLMNAACHEKDM4EALDH1A1 | |
| SCHEMBL7490236 | 0.81 | CACNB4 (0.37) | ABCB1ACHEKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0791000-B1 | THIENOPYRIDINE OR THIENOPYRIMIDINE DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-10-02 | — | — | EP | claimed |