Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 8/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 5/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7688280 | 0.93 | P2RX3 (0.45) | P2RX3MKNK1 | |
| SCHEMBL7491371 | 0.87 | HTR1A (0.42) | P2RX3MAPTNPSR1 | |
| SCHEMBL7490401 | 0.86 | NT5E (0.46) | MAPT | |
| SCHEMBL7489710 | 0.85 | KMT2A (0.42) | P2RX3 | |
| SCHEMBL7687913 | 0.84 | ACHE (0.43) | P2RX3 | |
| SCHEMBL7491349 | 0.81 | ACHE (0.38) | MAPT | |
| SCHEMBL7490236 | 0.80 | CACNB4 (0.37) | — | |
| SCHEMBL7684028 | 0.79 | CACNB4 (0.42) | MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL7487295 | 0.79 | LMNA (0.52) | MAPTSMN1; SMN2 | |
| SCHEMBL7489303 | 0.79 | CACNB4 (0.45) | MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900223-A1 | THIENOPYRIDINE DERIVATIVES AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 1999-03-10 | — | — | EP | disclosed |
| WO-1997040050-A1 | THIENOPYRIDINE DERIVATIVES AND THEIR USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |