Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | CCR3 | P51677 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7491243 | 0.82 | SLC6A3 (0.42) | SLC6A2CHRM1SLC6A4SLC6A3KCNH2 | |
| SCHEMBL8328605 | 0.79 | BCHE (0.43) | DRD2DRD4DRD3 | |
| SCHEMBL8331028 | 0.78 | BCHE (0.49) | DRD2DRD4DRD3 | |
| SCHEMBL7491968 | 0.74 | OPRK1 (0.44) | OPRK1MAPTLTA4HCCR3DRD3 | |
| SCHEMBL7493805 | 0.71 | OPRK1 (0.54) | OPRK1MAPTLTA4HCCR3CYP2D6 | |
| SCHEMBL7493799 | 0.71 | OPRK1 (0.54) | OPRK1MAPTLTA4HCCR3CYP2D6 | |
| SCHEMBL7491794 | 0.70 | DRD4 (0.41) | OPRK1MAPTSLC6A2SLC6A4LTA4H | |
| SCHEMBL7495709 | 0.70 | DRD4 (0.41) | OPRK1MAPTSLC6A2SLC6A4LTA4H | |
| SCHEMBL8329958 | 0.70 | DRD4 (0.41) | OPRK1MAPTSLC6A2SLC6A4LTA4H | |
| SCHEMBL7495991 | 0.70 | L3MBTL1 (0.33) | SLC6A2KCNH2LTA4HMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760362-B1 | DIAMINOMETHYLIDENE DERIVATIVE | NISSHIN SEIFUN GROUP INC (JP) | 2002-08-14 | — | — | EP | disclosed |
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0760362-A1 | NOVEL DIAMINOMETHYLIDENE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |