SCHEMBL7492873

SCHEMBL7492873

CCCNC1=Nc2sc(Cl)c(Br)c2SN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7564894 0.72
SCHEMBL7492877 0.69
SCHEMBL8715828 0.65 MAPT (0.30)
SCHEMBL8716334 0.59 LIMK1 (0.31)
SCHEMBL8716298 0.57 MMP3 (0.31)
SCHEMBL8720962 0.56 BCHE (0.35)
SCHEMBL8719264 0.56 ALDH1A1 (0.33)
SCHEMBL17635517 0.55
SCHEMBL25766951 0.54 ALDH1A1 (0.32)
SCHEMBL11553057 0.52 MAPK8 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1194430-A1 NOVEL PROCESS NOVO NORDISK A/S (DK) 2002-04-10 EP claimed
WO-2001002410-A1 NOVEL PROCESS NOVO NORDISK A/S (DK) 2001-01-11 WO claimed
EP-1194430-A1 NOVEL PROCESS NOVO NORDISK A/S (DK) 2002-04-10 EP disclosed
WO-2001002410-A1 NOVEL PROCESS NOVO NORDISK A/S (DK) 2001-01-11 WO disclosed